SGM Symposium 66: Prokaryotic Diversity: Mechanisms and Significance
Edited by N. A. Logan, H. M. Lappin-Scott & P. C. F. Oyston.
Published April 2006 by Cambridge
The true extent of prokaryote diversity, encompassing the spectrum of variability among bacteria, remains unknown.
Early discussions on prokaryote diversity were frequently devoted to sterile arguments about 'how much?' or 'how many?'. Increasingly,
however, the focus is turning towards trying to understand why prokaryote diversification occurs, its underlying mechanisms, and its likely
impact. The significance of such studies has a broad appeal, and the popular scientific press frequently highlights such topics as the emergence
of new diseases, the attribution of existing diseases to hitherto unrealized actions of prokaryotes, and the activities of prokaryotes in key
environmental processes. The dynamic nature of the prokaryotic world, and continuing advances in the technological tools available to this
Þeld of study, ensure that the latest story illustrating prokaryote diversity is never far away. This book will appeal to a wide variety of
microbiologists. Its coverage ranges from studies of prokaryotes in specialized environmental niches to broad examinations of prokaryote
evolution and diversity, and the mechanisms underlying them. Topics include: bacteria of the gastrointestinal tract, unculturable organisms
in the mouth and in the soil, the question of a link between chlamydia and heart disease, organisms from extreme environments, the diversity
of archaea and their phages, comparative genomics and the emergence of pathogens, spread of genomic islands between clinical and environmental
organisms, core genes, minimal genomes needed for life, horizontal gene transfer, genomic islands and the evolution of catabolic pathways,
phenotypic innovation, and patterns and extent of biodiversity.
SGM Symposium 65: Micro-organisms and Earth systems - advances in geomicrobiology
Edited by G. M. Gadd, K. T. Semple & H. M. Lappin-Scott.
Published September 2005 by Cambridge
There is growing awareness that important environmental transformations are catalysed, mediated and influenced by micro-organisms, and such knowledge is
having an increasing influence on disciplines other than microbiology, such as
geology and mineralogy. Geomicrobiology can be defined as the study of the role that
microbes have played and are playing in processes of fundamental importance to geology. As such, it is a truly inter-disciplinary subject area, necessitating input from
physical, chemical and biological sciences. The book focuses on some important microbial functions in aquatic and terrestrial environments and their influence on 'global'
processes and includes state-of-the-art approaches to visualization, culture and identification, community interactions and gene transfer, and diversity studies in relation
to key processes. Microbial involvement in key global biogeochemical cycles is exemplified by aquatic and terrestrial examples. All major groups of geochemically active
microbes are represented, including cyanobacteria, bacteria, archaea, microalgae and fungi, in a wide range of habitats, reflecting the wealth of diversity in both the
natural and the microbial world. This book represents environmental microbiology in its broadest sense and will help to promote exciting collaborations between
microbiologists and those in complementary physical and chemical disciplines.
SGM Symposium 64: Molecular Pathogenesis of Virus Infections
Edited by P. Digard, A. A. Nash & R. E. Randall.
Published April 2005 by Cambridge
Virus and prion diseases remain a major public health threat, in both developed and developing countries.
The worldwide HIV pandemic is but one example of a newly emerged virus disease; other potential threats come from exotic viruses such as
SARS, Ebola and Hantaan viruses. Older human viruses such as influenza, papilloma, herpes and the hepatitis viruses still cause major health problems.
Furthermore, as well as causing acute infections, some viruses may also establish persistent infections which can lead to the development of chronic
diseases, including cancer. This symposium book covers central factors that influence the pathogenicity of virus and prion infections.
Topics range from innate and adaptive immune responses and virus evasion of host defences to details of selected virus-host interactions,
including those involving dengue virus, HIV, influenza viruses, coronaviruses, hepatitis C virus, herpesviruses, papillomaviruses,
African swine fever virus and poxviruses.
SGM Symposium 63: Microbe-Vector Interactions in Vector-borne Diseases
Edited by S.H. Gillespie, G.L. Smith & A. Osbourn.
Published March 2004 by Cambridge
Several billion people are at daily risk of life-threatening vector-borne
diseases such as malaria, trypanosomiasis and dengue, and the dark shadow of
plague hovers in the few endemic foci where it waits ready to re-emerge in a
deadly pandemic. The abortive attempt to control malaria in the 1960s showed us
the problem that we face in eradicating vector-borne diseases. Research into
these tropical diseases fell into neglect during the 1960s, but in the 1970s
research was once more directed towards vector-borne diseases and more recent
initiatives such as the Roll Back Malaria Campaign have kept them in the
international spotlight. If we are not to repeat the mistakes of the past it
will be necessary to use all of our knowledge of vector biology.
Written by international researchers in the field this volume describes the
way in which pathogens interact with the vectors that transmit them. It details
the elegant biological adaptations that have enabled pathogens to live with
their vectors and in some circumstances control them. This knowledge has led to
new control strategies in the form of antibiotics and new vaccines which are
targeted not at the pathogen but at its vector. The recent epidemic of West
Nile virus infection in the United States and of Nipah virus in Malaysia
suggests that vector-borne diseases are of growing concern to everyone.
Microbe-Vector Interactions in Vector-borne Diseases is essential
reading for researchers and clinicians working with these diseases.
SGM Symposium 62:
Microbial Subversion of Host Cells
Edited by C.D. O'Connor and D.G.E. Smith.
Published April 2003 by Cambridge
This volume reviews the exciting new discipline of
cellular microbiology, reflecting both the explosion of knowledge in this
area and the realization that it provides wider insights into fundamental
cellular processes. The authors, chosen for their contributions to the
field, cover all the salient aspects using a range of different
Microbes have co-evolved with other organisms for
eons, to the extent that some are so acquainted with host cell biology
that they subvert key cellular processes with unrivalled precision.
Pathogenic bacteria and viruses, for example, are extremely adept at
intercepting host signal transduction pathways, re-routing protein
traffic, remodelling the cytoskeleton and influencing host cell
differentiation or death. Symbionts and commensal organisms, too, have
evolved sophisticated strategies to derive benefit from the host
environment without eliciting responses that compromise their viability.
While we are only just beginning to understand how microbes carry out such
manipulations of host cells, information in this area is accelerating
spectacularly. This timely book summarizes current knowledge and will
stimulate further research in this important area.
SGM Symposium 61:
Signals, Switches, Regulons and Cascades: Control of Bacterial Gene
Edited by D.A. Hodgson and C.M. Thomas.
Published April 2002 by Cambridge
DNA sequencing has provided a wealth of information
on the genetic material stored in bacterial genomes. The use of DNA arrays
and proteomics will transform the scale of our ability to describe the
patterns of gene expression as bacteria respond to their environments.
However, the ability to control bacteria in a clinical context or exploit
them in industrial or environmental contexts also depends on understanding
the regulatory mechanisms which connect input experience to output
response at the genetic level. This book deals with our current knowledge
of the circuits and networks that govern bacterial gene expression - from
the single gene to the whole genome - and which provide the framework for
explaining the data from the post-genomics revolution.
SGM Symposium 60:
New Challenges to Health: the Threat of Virus Infection
Edited by G.L. Smith, W.L. Irving, J.W. McCauley
and D.J. Rowlands.
Published March 2001 by Cambridge
Viruses continually evolve and adapt, posing new
threats to health. This book discusses the ecology of viruses including
the emergence of devastating haemorrhagic disease, and reviews the
molecular and cell biological basis of the pathogenesis of several virus
diseases. An introduction is given to the mathematical analysis of
recurrent epidemic virus disease, such as measles. Neurological and
psychological disease is discussed in relation to the pathological
mechanisms that may underlie prion disease (such as new variant CJD) and
to the possible virus involvement in human psychiatric illness. Virus
infections that have come to prominence recently (HIV, bunyaviruses,
morbilliviruses and caliciviruses) or that remain a threat (influenza and
hepatitis viruses) are discussed. There are also chapters on new and
potential niches for virus infections in the immunocompromised, and the
problem of the emergence of antiviral drug resistance in viruses for which
SGM Symposium 59:
Community Structure and Co-operation in Biofilms
Edited by D.G. Allison, P. Gilbert, H.M. Lappin-Scott and M.
Published September 2000 by Cambridge
The study of biofilm considers the close
association of micro-organisms with each other at interfaces and the
consequent physiological adaptation to the proximity of other cells and
surfaces. As such it is relevant to a variety of disciplines, including
medicine, dentistry, bioremediation, biofouling, water technology,
engineering and food science. Although the habitats studied, and their
associated cellular communities, differ widely, some common elements exist
such as method of attachment, coadhesion, regulation of biofilm phenotype
and biofilm architecture. This book aims to distil the common principles
of biofilm physiology and growth for all interested disciplines. It will
appeal to the specialist biofilm researcher as well as to students wishing
to introduce themselves to the topic.
Symposium Volume: Fighting Infection in the 21st Century
Edited by P.W. Andrew, P. Oyston, G.L. Smith and
Published October 2000 by Blackwell Science.
Full price £65. Discounted price to SGM or SfAM members
£39 (membership number required). Postage extra.
Orders to Science Marketing Department, Blackwell Science Ltd,
Osney Mead, Oxford OX2 0EL. Tel 01865 206013, fax 01865 721205.
The 20th century saw improvements in public health
and disease prevention which have had a dramatic impact on our lives.
Success in preventing infection by vaccination and treating infection with
antibiotics led some to believe that infectious disease was a thing of the
past. However, the adaptability of pathogens and the emergence of new
diseases have presented microbiologists with a new set of challenges as we
enter the new millennium. While celebrating past successes and
highlighting developing problems, this volume aims to address some of the
issues facing microbiologists in the future. Covering a wide range of
topics, it will provide an invaluable resource for microbiologists and an
excellent reference for advanced students.
Last updated 6 April 2006